Review



afatinib  (Tocris)


Bioz Verified Symbol Tocris is a verified supplier
Bioz Manufacturer Symbol Tocris manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93

    Structured Review

    Tocris afatinib
    Afatinib, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/Afatinib+dimaleate/pm41595226-87-0-8
    Average 93 stars, based on 7 article reviews
    afatinib - by Bioz Stars, 2026-09
    93/100 stars

    Images

    Related Articles

    Inhibition:

    Article Title: Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury.
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).. Afatinib dimaleate (EGFR, ErbB2, HER4/receptor tyrosine kinase 4), IWP 2 (inhibitor of Wnt production 2, targeting porcupine), SB 431542 (TGFbRI), and ITD 1 (1,4-dihydropyridine inducer of TGFbRII degradation-1) were purchased from Tocris (Minneapolis, MN).. Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).

    Article Title: Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).. Afatinib dimaleate (EGFR, ErbB2, ErbB4) was purchased from Tocris (Minneapolis, Minnesota).. Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).

    Passaging:

    Article Title: Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury.
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).. Afatinib dimaleate (EGFR, ErbB2, HER4/receptor tyrosine kinase 4), IWP 2 (inhibitor of Wnt production 2, targeting porcupine), SB 431542 (TGFbRI), and ITD 1 (1,4-dihydropyridine inducer of TGFbRII degradation-1) were purchased from Tocris (Minneapolis, MN).. Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).

    Article Title: Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).. Afatinib dimaleate (EGFR, ErbB2, ErbB4) was purchased from Tocris (Minneapolis, Minnesota).. Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).

    Activation Assay:

    Article Title: Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury.
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).. Afatinib dimaleate (EGFR, ErbB2, HER4/receptor tyrosine kinase 4), IWP 2 (inhibitor of Wnt production 2, targeting porcupine), SB 431542 (TGFbRI), and ITD 1 (1,4-dihydropyridine inducer of TGFbRII degradation-1) were purchased from Tocris (Minneapolis, MN).. Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).

    Article Title: Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).. Afatinib dimaleate (EGFR, ErbB2, ErbB4) was purchased from Tocris (Minneapolis, Minnesota).. Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).

    Expressing:

    Article Title: Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury.
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).. Afatinib dimaleate (EGFR, ErbB2, HER4/receptor tyrosine kinase 4), IWP 2 (inhibitor of Wnt production 2, targeting porcupine), SB 431542 (TGFbRI), and ITD 1 (1,4-dihydropyridine inducer of TGFbRII degradation-1) were purchased from Tocris (Minneapolis, MN).. Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).

    Article Title: Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).. Afatinib dimaleate (EGFR, ErbB2, ErbB4) was purchased from Tocris (Minneapolis, Minnesota).. Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).

    Staining:

    Article Title: Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury.
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).. Afatinib dimaleate (EGFR, ErbB2, HER4/receptor tyrosine kinase 4), IWP 2 (inhibitor of Wnt production 2, targeting porcupine), SB 431542 (TGFbRI), and ITD 1 (1,4-dihydropyridine inducer of TGFbRII degradation-1) were purchased from Tocris (Minneapolis, MN).. Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).

    Article Title: Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).. Afatinib dimaleate (EGFR, ErbB2, ErbB4) was purchased from Tocris (Minneapolis, Minnesota).. Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).

    Microscopy:

    Article Title: Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury.
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, TX), and TWS119 (GSK3b) and SP600125 (JNK) from ChemCruz (Dallas, TX).. Afatinib dimaleate (EGFR, ErbB2, HER4/receptor tyrosine kinase 4), IWP 2 (inhibitor of Wnt production 2, targeting porcupine), SB 431542 (TGFbRI), and ITD 1 (1,4-dihydropyridine inducer of TGFbRII degradation-1) were purchased from Tocris (Minneapolis, MN).. Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).Recombinant human heparin-binding EGF-like growth factor (HB-EGF), epigen (EPGN), neuregulin 1 (NRG1), amphiregulin (AREG), recombinant human transforming growth factor b2 (TGFb2), and recombinant human secreted frizzled related protein-1 were purchased from R&D Systems (Minneapolis, MN).

    Article Title: Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
    Article Snippet: AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).AZD 8931 (EGFR, ErbB2, ErbB3) was purchased from APExBIO (Houston, Texas), and TWS119 (GSK3β) and SP600125 (JNK) from ChemCruz (Dallas, Texas).. Afatinib dimaleate (EGFR, ErbB2, ErbB4) was purchased from Tocris (Minneapolis, Minnesota).. Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).Recombinant human heparin-binding (HB)-EGF and EPGN were purchased from R&D Systems (Minneapolis, Minnesota).



    Similar Products

    95
    MedChemExpress afatinib dimaleate
    Afatinib Dimaleate, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/Afatinib/pm42025967-70-48-70
    Average 95 stars, based on 1 article reviews
    afatinib dimaleate - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    96
    Selleck Chemicals afatinib dimaleate
    Afatinib Dimaleate, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/Afatinib/pm41828359-80-40-56
    Average 96 stars, based on 1 article reviews
    afatinib dimaleate - by Bioz Stars, 2026-09
    96/100 stars
      Buy from Supplier

    93
    Tocris afatinib
    Afatinib, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/Afatinib+dimaleate/pm41595226-87-0-8
    Average 93 stars, based on 1 article reviews
    afatinib - by Bioz Stars, 2026-09
    93/100 stars
      Buy from Supplier

    86
    Boehringer Ingelheim afatinib dimaleate
    Afatinib Dimaleate, supplied by Boehringer Ingelheim, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/afatinib/10__1016_slash_j__jfluchem__2026__110527-236-0-5
    Average 86 stars, based on 1 article reviews
    afatinib dimaleate - by Bioz Stars, 2026-09
    86/100 stars
      Buy from Supplier

    86
    Boehringer Ingelheim bibw 2992 ma2 dimaleate
    Bibw 2992 Ma2 Dimaleate, supplied by Boehringer Ingelheim, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/2992+bibw/fda_document____drugsatfda_docs_slash_nda_slash_2013_slash_201292orig1s000pharmr-793-32-5
    Average 86 stars, based on 1 article reviews
    bibw 2992 ma2 dimaleate - by Bioz Stars, 2026-09
    86/100 stars
      Buy from Supplier

    93
    Selleck Chemicals afatinib
    Afatinib, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/Afatinib+(BIBW2992)+Dimaleate/pm40579589-360-0-22
    Average 93 stars, based on 1 article reviews
    afatinib - by Bioz Stars, 2026-09
    93/100 stars
      Buy from Supplier

    90
    Boehringer Ingelheim afatinib dimaleate tablet
    Afatinib Dimaleate Tablet, supplied by Boehringer Ingelheim, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/afatinib+dimaleate/afatinib+dimaleate/pm40481213-44-25-29
    Average 90 stars, based on 1 article reviews
    afatinib dimaleate tablet - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    Image Search Results